Report Code : CVMI24072927 | Published Date : July 16, 2024
1 | Market Overview
The European continuous bioprocessing market involves the adoption of uninterrupted, integrated biomanufacturing technologies for the production of biologics, vaccines, and cell and gene therapies. Unlike traditional batch processing, continuous bioprocessing enables real-time production control, reduces footprint, lowers costs, and accelerates time-to-market for biopharmaceuticals.
Europe’s biologics manufacturing industry is increasingly adopting continuous bioprocessing to enhance efficiency and satisfy the rising demand for monoclonal antibodies (mAbs), recombinant proteins, and personalized medicine. This transition is bolstered by innovations in single-use systems, perfusion bioreactors, continuous chromatography, and process analytics.
2 | Market Size and Forecast
Year |
Market Value (USD Million) |
Notes |
2019 |
490 |
Driven by perfusion and PAT adoption |
2024 |
770 |
CAGR 9.5% (2019–2024) |
2031 |
1,780 |
Projected CAGR 12.4% (2024–2031) |
3 | Drivers & Challenges
Drivers:
- Rising demand for efficient, scalable biologics production
- Regulatory support for continuous manufacturing (EMA, PIC/S)
- Shift toward personalized therapies and smaller batch sizes
- Cost, speed, and flexibility benefits over batch processing
Challenges:
- High capital costs for facility retrofitting and technology integration
- Lack of skilled workforce and process validation expertise
- Concerns about robustness and process control in multiproduct facilities
4 | Segment Insights
By Technology:
- Continuous Upstream Bioprocessing (Perfusion Bioreactors)
- Continuous Downstream Bioprocessing (Chromatography, Filtration)
- Integrated Continuous Biomanufacturing (ICB)
- Process Analytical Technologies (PAT)
By Product Type:
- Monoclonal Antibodies (mAbs)
- Recombinant Proteins
- Vaccines
- Cell and Gene Therapy Products
5 | Regional Insights
- Germany & Switzerland (38%) – Strong pharma manufacturing and R&D hubs
- UK & Ireland (XX%) – Biotech innovation and CDMO investments
- France, Italy & Benelux (XX%) – Biomanufacturing expansion
- Nordics & CEE (XX%) – Fast-growing biotech and biosimilar clusters
6 | Competitive Landscape
Leading players include: Sartorius AG, Merck KGaA, GE Healthcare, Thermo Fisher Scientific, Lonza, Cytiva, MilliporeSigma, Pall Corporation, and Repligen.
Focus areas:
- Continuous chromatography skids
- Modular biomanufacturing platforms
- Bioprocess automation and AI-driven control systems
- Single-use perfusion systems for mid-scale production
Reasons To Buy

Scope

Key Players
- GE Healthcare
- Sartorius AG
- Merck KGaA
- Thermo Fisher Scientific
- Danaher Corporation
- Repligen Corporation
- Eppendorf AG
- 3M Company
- Corning Incorporated
- Getinge AB
- Bionet
Europe Continuous Bioprocessing Market Report
- 1. Europe Continuous Bioprocessing Market Research Report
- 1.1 Study Objectives
- 1.2 Europe Continuous Bioprocessing Market - Overview
- 1.3 Reason to Read This Report
- 1.4 Methodology and Forecast Analysis
- 2. Europe Continuous Bioprocessing Market Research Report - Preface
- 2.1 Europe Continuous Bioprocessing Market Research Report – Detailed Scope and Definitions
- 2.1.1 By Technology
- 2.1.2 By Product Type
- 2.1.3 By Region
- 2.1 Europe Continuous Bioprocessing Market Research Report – Detailed Scope and Definitions
- 3. Europe Continuous Bioprocessing Market Dynamics
- 3.1. Drivers - Macro-Economic Based, Supply Side, and Demand Side Drivers
- 3.2. Restraints – By Technology, By Product Type, By Country
- 3.3. Opportunities – By Technology, By Product Type, By Country
- 3.4. Trends – By Technology, By Product Type, By Country
- 3.5. PEST Analysis
- 3.6. Porters Five Rule Analysis
- 3.7. Company’s Share Analysis (CSA) by Region or By Country
- 3.8. Europe Continuous Bioprocessing Market Research Report – DROTs Impact Analysis
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- 4. Europe Continuous Bioprocessing Market Research Report, Historic Data 2019 - 2023 and Forecast Analysis Data 2024 - 2031
- 4.1. Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 4.2. Annual Market Trend Assessment – Year-on-Year (YoY) Growth Analysis (%)
- 4.3. Incremental Market Value/Volume Opportunity between 2019 - 2023 and 2024 - 2031
- 4.4. Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 5. Europe Continuous Bioprocessing Market, By Technology, 2019 - 2023 and Forecast, 2024 - 2031 (Market Value, In USD Mn)
- 5.1 Continuous Upstream Bioprocessing (Perfusion Bioreactors)
- 5.1.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 5.1.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 5.1.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 5.1.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 5.2 Continuous Downstream Bioprocessing (Chromatography, Filtration)
- 5.2.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 5.2.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 5.2.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 5.2.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 5.3 Integrated Continuous Biomanufacturing (ICB)
- 5.3.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 5.3.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 5.3.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 5.3.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 5.4 Process Analytical Technologies (PAT)
- 5.4.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 5.4.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 5.4.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 5.4.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 6.1 Monoclonal Antibodies (mAbs)
- 6.1.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 6.1.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 6.1.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 6.1.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 6.2 Recombinant Proteins Vaccines Cell
- 6.2.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 6.2.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 6.2.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 6.2.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 6.3 Gene Therapy Products
- 6.3.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 6.3.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 6.3.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 6.3.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 7. Europe Continuous Bioprocessing Market Forecast, By Region, 2019 - 2023 and 2024 - 2031 (Market Value, In USD Mn)
- 7.1 Europe
- 7.1.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 7.1.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 7.1.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 7.1.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 7.1 Europe
- 8. Europe Europe Continuous Bioprocessing Market Analysis, 2019 - 2023 and Forecast, 2024 - 2031 (Market Value, In USD Mn)
- 8.1 By Technology Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
- 8.1.1 Continuous Upstream Bioprocessing (Perfusion Bioreactors)
- 8.1.2 Continuous Downstream Bioprocessing (Chromatography, Filtration)
- 8.1.3 Integrated Continuous Biomanufacturing (ICB)
- 8.1.4 Process Analytical Technologies (PAT)
- 8.2.1 Monoclonal Antibodies (mAbs)
- 8.2.2 Recombinant Proteins Vaccines Cell
- 8.2.3 Gene Therapy Products
- 8.3.1 Germany
- 8.3.2 Uk
- 8.3.3 France
- 8.3.4 Spain
- 8.3.5 Italy
- 8.3.6 Russia
- 8.3.7 Rest of Europe
- 8.4 Europe Europe Continuous Bioprocessing Market – Opportunity Analysis Index, By Technology, By Product Type, and Country, 2024 - 2031
- 8.5 Regional Trends Analysis
- 8.6 Europe Europe Continuous Bioprocessing Market Research Report - Company Profiles
- 8.6.1 Company 1 (Germany)
- 8.6.2 Company 2 (Uk)
- 8.6.3 Company 3 (Uk)
- 9.1 Strategic Dashboard of Top Market Players
- 9.2 Company Profiles (Introduction, Financial Assessments, Portfolio of Offerings, Milestones and Achievements, Strategic Initiative, and SWOT Analysis)
- 9.2.1 GE Healthcare
- 9.2.2 Sartorius AG
- 9.2.3 Merck KGaA
- 9.2.4 Thermo Fisher Scientific
- 9.2.5 Danaher Corporation
- 9.2.6 Repligen Corporation
- 9.2.7 Eppendorf AG
- 9.2.8 3M Company
- 9.2.9 Corning Incorporated
- 9.2.10 Getinge AB
- 9.2.11 Bionet
- 8.1 By Technology Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
- 10. Data Collection Method and Research Approach
- 11. Principal Presumptions and Acronyms