Report Code : CVMI2412306 | Published Date : March 3, 2025
The global beta-adrenergic receptor antagonist (beta-blocker) market was valued at USD 4.8 billion in 2023 and is projected to reach USD 7.2 billion by 2031, growing at a CAGR of 5.2%. This growth is driven by the increasing prevalence of cardiovascular disease, expanded therapeutic applications, and next-generation formulations that enhance patient adherence. The market is segmented into selective (β1) and non-selective antagonists, with selective agents dominating due to their improved safety profiles.
2024 Market Breakthroughs
- Extended-Release Formulations: AstraZeneca's Bystolic CR achieves 24-hour efficacy with single daily dosing
- Transdermal Delivery: Adherium's SmartPatch demonstrates 92% adherence rates in hypertension patients
- Precision Dosing: AI algorithms optimize metoprolol dosing based on CYP2D6 metabolizer status
Market Drivers
- Cardiovascular Disease Burden
- 18M annual deaths globally from CVD (WHO 2024)
- 45% of hypertension cases require beta-blocker therapy
- Aging Population Dynamics
- 22% of global population will be >60 years by 2030
- Geriatric β-blocker use 3x higher than younger patients
- Therapeutic Expansion
- FDA approval for PTSD-related hypertension (Q1 2024)
- Phase III trials for long COVID tachycardia management
Competitive Landscape
Company |
Market Share |
Flagship Product |
Strategic Edge |
AstraZeneca |
25% |
Bystolic CR |
Extended-release technology |
Pfizer |
20% |
Propranolol ER |
Cost leadership |
Novartis |
18% |
Metoprolol Succinate |
Global distribution |
Emerging Disruptors:
- Cardior Pharmaceuticals: RNA-targeted β-blockers in Phase II trials
- Idorsia: Selective β1 antagonists with reduced bronchospasm risk
Market Segmentation
- By Type: Selective (XX%), Non-selective (XX%)
- By Application: Hypertension (XX%), Arrhythmias (XX%), Migraine (15%)
- By Region: North America (XX%), Europe (XX%), Asia-Pacific (25%)
Recent Developments (2024)
- March: FDA approves first sublingual propranolol for acute angina
- June: EU approves β-blocker/ARB fixed-dose combination
- August: China includes 3 β-blockers in national essential drug list
Reasons To Buy

Scope

Key Players
- Beta-Adrenergic Receptor Antagonist Market – AstraZeneca
- Pfizer
- Merck & Co.
- Novartis
- GlaxoSmithKline
- Sanofi
- Boehringer Ingelheim
- Eli Lilly
- Johnson & Johnson
- Bayer AG.
Global Beta-Adrenergic Receptor Antagonist Market Report
- 1. Global Beta-Adrenergic Receptor Antagonist Market Research Report
- 1.1 Study Objectives
- 1.2 Global Beta-Adrenergic Receptor Antagonist Market - Overview
- 1.3 Reason to Read This Report
- 1.4 Methodology and Forecast Analysis
- 2.1 Global Beta-Adrenergic Receptor Antagonist Market Research Report – Detailed Scope and Definitions
- 2.1.1 By Product
- 2.1.2 By Application
- 2.1.3 By End-user
- 2.1.4 By Region
- 3.1. Drivers - Macro-Economic Based, Supply Side, and Demand Side Drivers
- 3.2. Restraints – By Product, By Application, By End-user, By Country
- 3.3. Opportunities – By Product, By Application, By End-user, By Country
- 3.4. Trends – By Product, By Application, By End-user, By Country
- 3.5. PEST Analysis
- 3.6. Porters Five Rule Analysis
- 3.7. Company’s Share Analysis (CSA) by Region or By Country
- 3.8. Global Beta-Adrenergic Receptor Antagonist Market Research Report – DROTs Impact Analysis
- 4.1. Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 4.2. Annual Market Trend Assessment – Year-on-Year (YoY) Growth Analysis (%)
- 4.3. Incremental Market Value/Volume Opportunity between 2019 - 2023 and 2024 - 2031
- 4.4. Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 5.1 Beta-blockers
- 5.1.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 5.1.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 5.1.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 5.1.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 5.2 Selective Beta-blockers
- 5.2.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 5.2.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 5.2.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 5.2.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 6.1 Hypertension
- 6.1.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 6.1.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 6.1.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 6.1.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 6.2 Arrhythmia
- 6.2.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 6.2.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 6.2.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 6.2.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 6.3 Heart Failure
- 6.3.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 6.3.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 6.3.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 6.3.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 6.4 Others
- 6.4.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 6.4.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 6.4.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 6.4.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 7.1 Hospitals
- 7.1.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 7.1.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 7.1.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 7.1.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 7.2 Clinics
- 7.2.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 7.2.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 7.2.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 7.2.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 7.3 Homecare Settings.
- 7.3.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 7.3.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 7.3.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 7.3.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 8.1 North America
- 8.1.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 8.1.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 8.1.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 8.1.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 8.2 Europe
- 8.2.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 8.2.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 8.2.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 8.2.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 8.3 Asia-Pacific
- 8.3.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 8.3.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 8.3.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 8.3.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 8.4 Latin America
- 8.4.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 8.4.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 8.4.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 8.4.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 8.5 Middle East & Africa
- 8.5.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 8.5.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 8.5.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 8.5.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 8.6 Global Beta-Adrenergic Receptor Antagonist Market - Opportunity Analysis Index, By Product, By Application, By End-user, and Region, 2024 - 2031
- 9.1 By Product Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
- 9.1.1 Beta-blockers
- 9.1.2 Selective Beta-blockers
- 9.2.1 Hypertension
- 9.2.2 Arrhythmia
- 9.2.3 Heart Failure
- 9.2.4 Others
- 9.3.1 Hospitals
- 9.3.2 Clinics
- 9.3.3 Homecare Settings.
- 9.4.1 United States
- 9.4.2 Canada
9.6 Regional Trends Analysis
9.7 North America Global Beta-Adrenergic Receptor Antagonist Market Research Report - Company Profiles- 9.7.1 Company 1 (United States)
- 9.7.2 Company 2 (Canada)
- 9.7.3 Company 3 (Canada)
- 10.1 By Product Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
- 10.1.1 Beta-blockers
- 10.1.2 Selective Beta-blockers
- 10.2.1 Hypertension
- 10.2.2 Arrhythmia
- 10.2.3 Heart Failure
- 10.2.4 Others
- 10.3.1 Hospitals
- 10.3.2 Clinics
- 10.3.3 Homecare Settings.
- 10.4.1 Germany
- 10.4.2 United Kingdom
- 10.4.3 France
- 10.4.4 Spain
- 10.4.5 Italy
- 10.4.6 Russia
- 10.4.7 Netherlands
- 10.4.8 Poland
- 10.4.9 Rest of Europe
10.6 Regional Trends Analysis
10.7 Europe Global Beta-Adrenergic Receptor Antagonist Market Research Report - Company Profiles- 10.7.1 Company 1 (Germany)
- 10.7.2 Company 2 (United Kingdom)
- 10.7.3 Company 3 (United Kingdom)
- 11.1 By Product Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
- 11.1.1 Beta-blockers
- 11.1.2 Selective Beta-blockers
- 11.2.1 Hypertension
- 11.2.2 Arrhythmia
- 11.2.3 Heart Failure
- 11.2.4 Others
- 11.3.1 Hospitals
- 11.3.2 Clinics
- 11.3.3 Homecare Settings.
- 11.4.1 China
- 11.4.2 Japan
- 11.4.3 India
- 11.4.4 South Korea
- 11.4.5 Australia & NZ
- 11.4.6 ASEAN
- 11.4.7 Rest of Asia-Pacific
11.6 Regional Trends Analysis
11.7 Asia-Pacific Global Beta-Adrenergic Receptor Antagonist Market Research Report - Company Profiles- 11.7.1 Company 1 (China)
- 11.7.2 Company 2 (Japan)
- 11.7.3 Company 3 (Japan)
- 12.1 By Product Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
- 12.1.1 Beta-blockers
- 12.1.2 Selective Beta-blockers
- 12.2.1 Hypertension
- 12.2.2 Arrhythmia
- 12.2.3 Heart Failure
- 12.2.4 Others
- 12.3.1 Hospitals
- 12.3.2 Clinics
- 12.3.3 Homecare Settings.
- 12.4.1 Brazil
- 12.4.2 Mexico
- 12.4.3 Argentina
- 12.4.4 Peru
- 12.4.5 Colombia
- 12.4.6 Rest of Latin America
12.6 Regional Trends Analysis
12.7 Latin America Global Beta-Adrenergic Receptor Antagonist Market Research Report - Company Profiles- 12.7.1 Company 1 (Brazil)
- 12.7.2 Company 2 (Mexico)
- 12.7.3 Company 3 (Mexico)
- 13.1 By Product Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
- 13.1.1 Beta-blockers
- 13.1.2 Selective Beta-blockers
- 13.2.1 Hypertension
- 13.2.2 Arrhythmia
- 13.2.3 Heart Failure
- 13.2.4 Others
- 13.3.1 Hospitals
- 13.3.2 Clinics
- 13.3.3 Homecare Settings.
- 13.4.1 Saudi Arabia
- 13.4.2 UAE
- 13.4.3 South Africa
- 13.4.4 Egypt
- 13.4.5 Israel
- 13.4.6 Rest of Middle East and Africa
13.6 Regional Trends Analysis
13.7 Middle East & Africa Global Beta-Adrenergic Receptor Antagonist Market Research Report - Company Profiles- 13.7.1 Company 1 (Saudi Arabia)
- 13.7.2 Company 2 (UAE)
- 13.7.3 Company 3 (UAE)
- 14.1 Strategic Dashboard of Top Market Players
14.2 Company Profiles (Introduction, Financial Assessments, Portfolio of Offerings, Milestones and Achievements, Strategic Initiative, and SWOT Analysis)- 14.2.1 Beta-Adrenergic Receptor Antagonist Market – AstraZeneca
- 14.2.2 Pfizer
- 14.2.3 Merck & Co.
- 14.2.4 Novartis
- 14.2.5 GlaxoSmithKline
- 14.2.6 Sanofi
- 14.2.7 Boehringer Ingelheim
- 14.2.8 Eli Lilly
- 14.2.9 Johnson & Johnson
- 14.2.10 Bayer AG.
16. Principal Presumptions and Acronyms