Report Code : CVMI2603252601501 | Published Date : March 30, 2025
The global cancer biomarkers market was valued at USD 18.6 billion in 2023 and is projected to reach USD 48.3 billion by 2031, growing at a 12.7% CAGR (ClearView Market Insights, 2024). The adoption of precision oncology, advancements in liquid biopsy, and AI-driven diagnostic platforms fuel this expansion.
2. Technological Breakthroughs (2024)
2.1 Liquid Biopsy Innovations
- Guardant360® CDx: Detects over 1,000 mutations from 10 mL of blood (FDA-approved).
- FOUNDATION ONE® Liquid: TMB/MSI profiling with 95% concordance vs tissue.
- Grail’s Galleri®: Multi-cancer early detection (MCED) for 50+ cancers.
2.2 AI/ML Integration
Platform |
Function |
Clinical Impact |
Paige Prostate |
AI pathology (99% sensitivity) |
Reduces false negatives by 45% |
Tempus xF |
Genomic + clinical data fusion |
30% faster therapy matching |
PathAI’s PD-L1 |
Automated scoring |
Cuts interpretation time by 70% |
2.3 Novel Biomarker Classes
- Exosomal Proteins: Caris Life Sciences’ ExoDx™ predicts therapy resistance.
- Methylation Signatures: Illumina’s TSO500 detects epigenetic drivers.
- Circulating Tumor DNA (ctDNA): Natera’s Signatera™ monitors recurrence.
3. Application-Specific Advances
3.1 Solid Tumors (XX% Market Share)
- NSCLC: Foundation Medicine’s tissue-free TMB validated for Keytruda®.
- Breast Cancer: Agendia’s MammaPrint® reduces chemo use by 38%.
3.2 Hematologic Malignancies (XX%)
- CLL: Adaptive’s ClonoSEQ® detects 1-in-1M MRD cells.
- AML: Invivoscribe’s LymphoTrack® IDs FLT3/IDH2 mutations.
3.3 Early Detection (XX%)
- Colorectal: Exact Sciences’ Cologuard® adoption hits 45% in Medicare.
- Pancreatic: Canary Foundation’s Early Test detects Stage I/II at 92% accuracy.
4. Competitive Landscape
Company |
Market Share |
Flagship Product |
2024 Launch |
Roche |
24% |
FoundationOne® Liquid |
TMB/MSI + HRD scoring |
Guardant Health |
19% |
Guardant360® CDx |
1,000+ mutation panel |
Exact Sciences |
15% |
Cologuard® |
Multi-cancer RNA signatures |
Natera |
12% |
Signatera™ |
ctDNA recurrence monitoring |
Emerging Players:
- Freenome: AI-powered multi-omics early detection.
- GRAIL: Galleri® MCED expanding to 50 cancers.
5. Regional Adoption
- North America (XX%): CMS coverage for Guardant360® drives uptake.
- Europe (32%): ESMO guidelines mandate NGS testing for all NSCLC.
- Asia-Pacific (XX%): China NMPA fast-tracks 10 liquid biopsy kits.
Reasons To Buy

Scope

Key Players
- Roche
- Thermo Fisher Scientific
- Abbott
- Bio-Rad Laboratories
- Qiagen
- Siemens Healthineers
- Agilent Technologies
Global Cancer Biomarkers Market Report
- 1. Global Cancer Biomarkers Market Research Report
- 1.1 Study Objectives
- 1.2 Global Cancer Biomarkers Market - Overview
- 1.3 Reason to Read This Report
- 1.4 Methodology and Forecast Analysis
- 2.1 Global Cancer Biomarkers Market Research Report – Detailed Scope and Definitions
- 2.1.1 By Type
- 2.1.2 By Application
- 2.1.3 By Cancer Type
- 2.1.4 By End-User
- 2.1.5 By Region
- 3.1. Drivers - Macro-Economic Based, Supply Side, and Demand Side Drivers
- 3.2. Restraints – By Type, By Application, By Cancer Type, By End-User, By Country
- 3.3. Opportunities – By Type, By Application, By Cancer Type, By End-User, By Country
- 3.4. Trends – By Type, By Application, By Cancer Type, By End-User, By Country
- 3.5. PEST Analysis
- 3.6. Porters Five Rule Analysis
- 3.7. Company’s Share Analysis (CSA) by Region or By Country
- 3.8. Global Cancer Biomarkers Market Research Report – DROTs Impact Analysis
- 4.1. Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 4.2. Annual Market Trend Assessment – Year-on-Year (YoY) Growth Analysis (%)
- 4.3. Incremental Market Value/Volume Opportunity between 2019 - 2023 and 2024 - 2031
- 4.4. Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 5.1 Protein Biomarkers
- 5.1.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 5.1.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 5.1.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 5.1.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 5.2 Genetic Biomarkers
- 5.2.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 5.2.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 5.2.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 5.2.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 5.3 Metabolic Biomarkers
- 5.3.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 5.3.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 5.3.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 5.3.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 6.1 Diagnostics
- 6.1.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 6.1.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 6.1.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 6.1.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 6.2 Prognostics
- 6.2.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 6.2.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 6.2.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 6.2.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 6.3 Drug Discovery & Development
- 6.3.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 6.3.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 6.3.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 6.3.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 7.1 Breast Cancer
- 7.1.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 7.1.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 7.1.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 7.1.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 7.2 Lung Cancer
- 7.2.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 7.2.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 7.2.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 7.2.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 7.3 Colorectal Cancer
- 7.3.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 7.3.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 7.3.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 7.3.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 7.4 Prostate Cancer
- 7.4.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 7.4.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 7.4.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 7.4.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 7.5 Others
- 7.5.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 7.5.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 7.5.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 7.5.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 8.1 Hospitals
- 8.1.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 8.1.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 8.1.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 8.1.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 8.2 Research Laboratories
- 8.2.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 8.2.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 8.2.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 8.2.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 8.3 Diagnostic Centers
- 8.3.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 8.3.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 8.3.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 8.3.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 9.1 North America
- 9.1.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 9.1.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 9.1.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 9.1.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 9.2 Europe
- 9.2.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 9.2.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 9.2.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 9.2.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 9.3 Asia-Pacific
- 9.3.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 9.3.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 9.3.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 9.3.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 9.4 Latin America
- 9.4.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 9.4.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 9.4.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 9.4.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 9.5 Middle East & Africa
- 9.5.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 9.5.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 9.5.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 9.5.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 9.6 Global Cancer Biomarkers Market - Opportunity Analysis Index, By Type, By Application, By Cancer Type, By End-User, and Region, 2024 - 2031
- 10.1 By Type Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
- 10.1.1 Protein Biomarkers
- 10.1.2 Genetic Biomarkers
- 10.1.3 Metabolic Biomarkers
- 10.2.1 Diagnostics
- 10.2.2 Prognostics
- 10.2.3 Drug Discovery & Development
- 10.3.1 Breast Cancer
- 10.3.2 Lung Cancer
- 10.3.3 Colorectal Cancer
- 10.3.4 Prostate Cancer
- 10.3.5 Others
- 10.4.1 Hospitals
- 10.4.2 Research Laboratories
- 10.4.3 Diagnostic Centers
- 10.5.1 United States
- 10.5.2 Canada
10.7 Regional Trends Analysis
10.8 North America Global Cancer Biomarkers Market Research Report - Company Profiles- 10.8.1 Company 1 (United States)
- 10.8.2 Company 2 (Canada)
- 10.8.3 Company 3 (Canada)
- 11.1 By Type Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
- 11.1.1 Protein Biomarkers
- 11.1.2 Genetic Biomarkers
- 11.1.3 Metabolic Biomarkers
- 11.2.1 Diagnostics
- 11.2.2 Prognostics
- 11.2.3 Drug Discovery & Development
- 11.3.1 Breast Cancer
- 11.3.2 Lung Cancer
- 11.3.3 Colorectal Cancer
- 11.3.4 Prostate Cancer
- 11.3.5 Others
- 11.4.1 Hospitals
- 11.4.2 Research Laboratories
- 11.4.3 Diagnostic Centers
- 11.5.1 Germany
- 11.5.2 United Kingdom
- 11.5.3 France
- 11.5.4 Spain
- 11.5.5 Italy
- 11.5.6 Russia
- 11.5.7 Netherlands
- 11.5.8 Poland
- 11.5.9 Rest of Europe
11.7 Regional Trends Analysis
11.8 Europe Global Cancer Biomarkers Market Research Report - Company Profiles- 11.8.1 Company 1 (Germany)
- 11.8.2 Company 2 (United Kingdom)
- 11.8.3 Company 3 (United Kingdom)
- 12.1 By Type Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
- 12.1.1 Protein Biomarkers
- 12.1.2 Genetic Biomarkers
- 12.1.3 Metabolic Biomarkers
- 12.2.1 Diagnostics
- 12.2.2 Prognostics
- 12.2.3 Drug Discovery & Development
- 12.3.1 Breast Cancer
- 12.3.2 Lung Cancer
- 12.3.3 Colorectal Cancer
- 12.3.4 Prostate Cancer
- 12.3.5 Others
- 12.4.1 Hospitals
- 12.4.2 Research Laboratories
- 12.4.3 Diagnostic Centers
- 12.5.1 China
- 12.5.2 Japan
- 12.5.3 India
- 12.5.4 South Korea
- 12.5.5 Australia & NZ
- 12.5.6 ASEAN
- 12.5.7 Rest of Asia-Pacific
12.7 Regional Trends Analysis
12.8 Asia-Pacific Global Cancer Biomarkers Market Research Report - Company Profiles- 12.8.1 Company 1 (China)
- 12.8.2 Company 2 (Japan)
- 12.8.3 Company 3 (Japan)
- 13.1 By Type Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
- 13.1.1 Protein Biomarkers
- 13.1.2 Genetic Biomarkers
- 13.1.3 Metabolic Biomarkers
- 13.2.1 Diagnostics
- 13.2.2 Prognostics
- 13.2.3 Drug Discovery & Development
- 13.3.1 Breast Cancer
- 13.3.2 Lung Cancer
- 13.3.3 Colorectal Cancer
- 13.3.4 Prostate Cancer
- 13.3.5 Others
- 13.4.1 Hospitals
- 13.4.2 Research Laboratories
- 13.4.3 Diagnostic Centers
- 13.5.1 Brazil
- 13.5.2 Mexico
- 13.5.3 Argentina
- 13.5.4 Peru
- 13.5.5 Colombia
- 13.5.6 Rest of Latin America
13.7 Regional Trends Analysis
13.8 Latin America Global Cancer Biomarkers Market Research Report - Company Profiles- 13.8.1 Company 1 (Brazil)
- 13.8.2 Company 2 (Mexico)
- 13.8.3 Company 3 (Mexico)
- 14.1 By Type Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
- 14.1.1 Protein Biomarkers
- 14.1.2 Genetic Biomarkers
- 14.1.3 Metabolic Biomarkers
- 14.2.1 Diagnostics
- 14.2.2 Prognostics
- 14.2.3 Drug Discovery & Development
- 14.3.1 Breast Cancer
- 14.3.2 Lung Cancer
- 14.3.3 Colorectal Cancer
- 14.3.4 Prostate Cancer
- 14.3.5 Others
- 14.4.1 Hospitals
- 14.4.2 Research Laboratories
- 14.4.3 Diagnostic Centers
- 14.5.1 Saudi Arabia
- 14.5.2 UAE
- 14.5.3 South Africa
- 14.5.4 Egypt
- 14.5.5 Israel
- 14.5.6 Rest of Middle East and Africa
14.7 Regional Trends Analysis
14.8 Middle East & Africa Global Cancer Biomarkers Market Research Report - Company Profiles- 14.8.1 Company 1 (Saudi Arabia)
- 14.8.2 Company 2 (UAE)
- 14.8.3 Company 3 (UAE)
- 15.1 Strategic Dashboard of Top Market Players
15.2 Company Profiles (Introduction, Financial Assessments, Portfolio of Offerings, Milestones and Achievements, Strategic Initiative, and SWOT Analysis)- 15.2.1 Roche
- 15.2.2 Thermo Fisher Scientific
- 15.2.3 Abbott
- 15.2.4 Bio-Rad Laboratories
- 15.2.5 Qiagen
- 15.2.6 Siemens Healthineers
- 15.2.7 Agilent Technologies
17. Principal Presumptions and Acronyms