Report Code : CVMI2603252601427 | Published Date : March 30, 2025

1 | Market Overview

The global chiral chromatography column market is experiencing significant growth, fueled by rising demand for enantiomeric purity in pharmaceuticals, agrochemicals, and food sectors. Chiral chromatography is an essential analytical technique employed to separate enantiomers in racemic mixtures, ensuring drug safety and effectiveness.

The expanding pharmaceutical industry fuels the market growth, stringent regulatory requirements for chiral purity, and advancements in column technologies like supercritical fluid chromatography (SFC) and high-performance liquid chromatography (HPLC). Additionally, increasing R&D in biotechnology and growing applications in forensic and environmental analysis are boosting demand.

 

2 | Market Size and Forecast

Year

Market Value (USD Billion)

Notes

2019

1.21

Historical benchmark

2024

2.06

Five-year CAGR 10.8%

2031

4.81

Seven-year CAGR 12.6%

The market is projected to more than double by 2031, supported by pharmaceutical R&D growth and advances in analytical technologies.

 

3 | Key Market Drivers

  • Stringent Regulatory Requirements for Chiral Drug Purity.
  • Growth in Pharmaceutical and Biopharmaceutical R&D.
  • Adoption of Supercritical Fluid Chromatography (SFC).
  • Increasing Applications in Agrochemicals and Food Testing.
  • Advancements in HPLC and UHPLC Column Technologies.

 

4 | Market Challenges

  • High Cost of Chiral Columns and Instrumentation.
  • Technical Complexity in Method Development.
  • Limited Skilled Workforce in Analytical Chemistry.
  • Competition from Alternative Separation Techniques.

 

5 | Competitive Landscape

The chiral chromatography column market is fairly consolidated, with main players emphasizing column innovation, tailored solutions, and strong supply chains.

Market Share Estimates (2024):

Company

Estimated Market Share

Key Products

Daicel Corporation

28%

CHIRALPAK®, CHIRALCEL® series

Agilent Technologies

22%

InfinityLab Poroshell® and ZORBAX® columns

Merck KGaA (MilliporeSigma)

17%

Supelco® CHIRALDEX® and Astec® chiral columns

Thermo Fisher Scientific

14%

Hypersil GOLD® and Accucore® columns

Others (Waters, Shimadzu, YMC, regional OEMs)

19%

Specialized columns and SFC solutions

 

6 | Market Segmentation
By Technique:

  • High-Performance Liquid Chromatography (HPLC)
  • Supercritical Fluid Chromatography (SFC)
  • Gas Chromatography (GC)
  • Others (Capillary Electrophoresis)

 

By End User:

  • Pharmaceutical & Biotechnology Companies
  • Academic & Research Institutes
  • Food & Beverage Testing Labs
  • Environmental Testing Labs
  • Contract Research Organizations (CROs)

 

By Region:

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East & Africa

 

7 | Strategic Outlook
Future market growth will be driven by the integration of AI-based method optimization, eco-friendly column materials, miniaturized chromatography systems, and expansion in emerging markets. Collaboration between instrument manufacturers and pharmaceutical companies will further accelerate innovation.





Reasons To Buy

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Scope

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Key Players

  • Shimadzu Corporation
  • Daicel Corporation
  • Thermo Fisher Scientific Inc.
  • Merck KGaA
  • Agilent Technologies Inc.
  • Waters Corporation
  • Bio‑Rad Laboratories Inc.
  • Danaher Corporation (Phenomenex Inc.)
  • GE Healthcare (General Electric Company)
  • PerkinElmer Inc.
  • Phenomenex Inc.
  • Tosoh Corporation
  • GL Sciences Inc.
  • YMC Co. Ltd.
  • Chiral Technologies Inc.

Chiral Chromatography Column Market Report


  1. 1. Chiral Chromatography Column Market Research Report
    1. 1.1 Study Objectives
    2. 1.2 Chiral Chromatography Column Market - Overview
    3. 1.3 Reason to Read This Report
    4. 1.4 Methodology and Forecast Analysis
  2. 2. Chiral Chromatography Column Market Research Report - Preface
    1. 2.1 Chiral Chromatography Column Market Research Report – Detailed Scope and Definitions
      1. 2.1.1 By Technique:
      2. 2.1.2 By End User:
      3. 2.1.3 By Region
  3. 3. Chiral Chromatography Column Market Dynamics
    1. 3.1. Drivers - Macro-Economic Based, Supply Side, and Demand Side Drivers
    2. 3.2. Restraints – By Technique:, By End User:, By Country
    3. 3.3. Opportunities – By Technique:, By End User:, By Country
    4. 3.4. Trends – By Technique:, By End User:, By Country
    5. 3.5. PEST Analysis
    6. 3.6. Porters Five Rule Analysis
    7. 3.7. Company’s Share Analysis (CSA) by Region or By Country
    8. 3.8. Chiral Chromatography Column Market Research Report – DROTs Impact Analysis
    1. 4. Chiral Chromatography Column Market Research Report, Historic Data 2019 - 2023 and Forecast Analysis Data 2024 - 2031
    2. 4.1. Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
    3. 4.2. Annual Market Trend Assessment – Year-on-Year (YoY) Growth Analysis (%)
    4. 4.3. Incremental Market Value/Volume Opportunity between 2019 - 2023 and 2024 - 2031
    5. 4.4. Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
  1. 5. Chiral Chromatography Column Market, By Technique:, 2019 - 2023 and Forecast, 2024 - 2031 (Market Value, In USD Mn)
    1. 5.1 High-Performance Liquid Chromatography (HPLC)
    2. 5.1.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
    3. 5.1.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
    4. 5.1.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
    5. 5.1.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
    6. 5.2 Supercritical Fluid Chromatography (SFC)
    7. 5.2.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
    8. 5.2.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
    9. 5.2.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
    10. 5.2.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
    11. 5.3 Gas Chromatography (GC)
    12. 5.3.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
    13. 5.3.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
    14. 5.3.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
    15. 5.3.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
    16. 5.4 Others (Capillary Electrophoresis)
    17. 5.4.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
    18. 5.4.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
    19. 5.4.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
    20. 5.4.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
    6. Chiral Chromatography Column Market, By End User:, 2019 - 2023 and Forecast, 2024 - 2031 (Market Value, In USD Mn)
    1. 6.1 Pharmaceutical & Biotechnology Companies
    2. 6.1.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
    3. 6.1.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
    4. 6.1.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
    5. 6.1.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
    6. 6.2 Academic & Research Institutes
    7. 6.2.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
    8. 6.2.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
    9. 6.2.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
    10. 6.2.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
    11. 6.3 Food & Beverage Testing Labs
    12. 6.3.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
    13. 6.3.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
    14. 6.3.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
    15. 6.3.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
    16. 6.4 Environmental Testing Labs
    17. 6.4.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
    18. 6.4.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
    19. 6.4.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
    20. 6.4.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
    21. 6.5 Contract Research Organizations (CROs)
    22. 6.5.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
    23. 6.5.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
    24. 6.5.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
    25. 6.5.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
  1. 7. Chiral Chromatography Column Market Forecast, By Region, 2019 - 2023 and 2024 - 2031 (Market Value, In USD Mn)
    1. 7.1 North America
      1. 7.1.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
      2. 7.1.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
      3. 7.1.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
      4. 7.1.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
      7.2 Europe
      1. 7.2.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
      2. 7.2.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
      3. 7.2.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
      4. 7.2.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
      7.3 Asia-Pacific
      1. 7.3.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
      2. 7.3.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
      3. 7.3.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
      4. 7.3.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
      7.4 Latin America
      1. 7.4.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
      2. 7.4.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
      3. 7.4.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
      4. 7.4.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
      7.5 Middle East and Africa
      1. 7.5.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
      2. 7.5.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
      3. 7.5.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
      4. 7.5.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
      7.6 Chiral Chromatography Column Market - Opportunity Analysis Index, By Technique:, By End User:, and Region, 2024 - 2031
  1. 8. North America Chiral Chromatography Column Market Analysis, 2019 - 2023 and Forecast, 2024 - 2031 (Market Value, In USD Mn)
    1. 8.1 By Technique: Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
      1. 8.1.1 High-Performance Liquid Chromatography (HPLC)
      2. 8.1.2 Supercritical Fluid Chromatography (SFC)
      3. 8.1.3 Gas Chromatography (GC)
      4. 8.1.4 Others (Capillary Electrophoresis)
      8.2 By End User: Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
      1. 8.2.1 Pharmaceutical & Biotechnology Companies
      2. 8.2.2 Academic & Research Institutes
      3. 8.2.3 Food & Beverage Testing Labs
      4. 8.2.4 Environmental Testing Labs
      5. 8.2.5 Contract Research Organizations (CROs)
      8.3 Country Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
      1. 8.3.1 United States
      2. 8.3.2 Canada
    2. 8.4 North America Chiral Chromatography Column Market – Opportunity Analysis Index, By Technique:, By End User:, and Country, 2024 - 2031
    3. 8.5 Regional Trends Analysis
    4. 8.6 North America Chiral Chromatography Column Market Research Report - Company Profiles
      1. 8.6.1 Company 1 (United States)
      2. 8.6.2 Company 2 (Canada)
      3. 8.6.3 Company 3 (Canada)
    9. Europe Chiral Chromatography Column Market Analysis, 2019 - 2023 and Forecast, 2024 - 2031 (Market Value, In USD Mn)
    1. 9.1 By Technique: Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
      1. 9.1.1 High-Performance Liquid Chromatography (HPLC)
      2. 9.1.2 Supercritical Fluid Chromatography (SFC)
      3. 9.1.3 Gas Chromatography (GC)
      4. 9.1.4 Others (Capillary Electrophoresis)
      9.2 By End User: Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
      1. 9.2.1 Pharmaceutical & Biotechnology Companies
      2. 9.2.2 Academic & Research Institutes
      3. 9.2.3 Food & Beverage Testing Labs
      4. 9.2.4 Environmental Testing Labs
      5. 9.2.5 Contract Research Organizations (CROs)
      9.3 Country Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
      1. 9.3.1 Germany
      2. 9.3.2 United Kingdom
      3. 9.3.3 France
      4. 9.3.4 Spain
      5. 9.3.5 Italy
      6. 9.3.6 Russia
    2. 9.4 Europe Chiral Chromatography Column Market – Opportunity Analysis Index, By Technique:, By End User:, and Country, 2024 - 2031
    3. 9.5 Regional Trends Analysis
    4. 9.6 Europe Chiral Chromatography Column Market Research Report - Company Profiles
      1. 9.6.1 Company 1 (Germany)
      2. 9.6.2 Company 2 (United Kingdom)
      3. 9.6.3 Company 3 (United Kingdom)
    10. Asia-Pacific Chiral Chromatography Column Market Analysis, 2019 - 2023 and Forecast, 2024 - 2031 (Market Value, In USD Mn)
    1. 10.1 By Technique: Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
      1. 10.1.1 High-Performance Liquid Chromatography (HPLC)
      2. 10.1.2 Supercritical Fluid Chromatography (SFC)
      3. 10.1.3 Gas Chromatography (GC)
      4. 10.1.4 Others (Capillary Electrophoresis)
      10.2 By End User: Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
      1. 10.2.1 Pharmaceutical & Biotechnology Companies
      2. 10.2.2 Academic & Research Institutes
      3. 10.2.3 Food & Beverage Testing Labs
      4. 10.2.4 Environmental Testing Labs
      5. 10.2.5 Contract Research Organizations (CROs)
      10.3 Country Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
      1. 10.3.1 China
      2. 10.3.2 Japan
      3. 10.3.3 India
      4. 10.3.4 South Korea
      5. 10.3.5 Australia & New Zealand
      6. 10.3.6 ASEAN
    2. 10.4 Asia-Pacific Chiral Chromatography Column Market – Opportunity Analysis Index, By Technique:, By End User:, and Country, 2024 - 2031
    3. 10.5 Regional Trends Analysis
    4. 10.6 Asia-Pacific Chiral Chromatography Column Market Research Report - Company Profiles
      1. 10.6.1 Company 1 (China)
      2. 10.6.2 Company 2 (Japan)
      3. 10.6.3 Company 3 (Japan)
    11. Latin America Chiral Chromatography Column Market Analysis, 2019 - 2023 and Forecast, 2024 - 2031 (Market Value, In USD Mn)
    1. 11.1 By Technique: Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
      1. 11.1.1 High-Performance Liquid Chromatography (HPLC)
      2. 11.1.2 Supercritical Fluid Chromatography (SFC)
      3. 11.1.3 Gas Chromatography (GC)
      4. 11.1.4 Others (Capillary Electrophoresis)
      11.2 By End User: Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
      1. 11.2.1 Pharmaceutical & Biotechnology Companies
      2. 11.2.2 Academic & Research Institutes
      3. 11.2.3 Food & Beverage Testing Labs
      4. 11.2.4 Environmental Testing Labs
      5. 11.2.5 Contract Research Organizations (CROs)
      11.3 Country Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
      1. 11.3.1 Brazil
      2. 11.3.2 Mexico
      3. 11.3.3 Argentina
      4. 11.3.4 Peru
      5. 11.3.5 Colombia
      6. 11.3.6 Rest of Latin America
    2. 11.4 Latin America Chiral Chromatography Column Market – Opportunity Analysis Index, By Technique:, By End User:, and Country, 2024 - 2031
    3. 11.5 Regional Trends Analysis
    4. 11.6 Latin America Chiral Chromatography Column Market Research Report - Company Profiles
      1. 11.6.1 Company 1 (Brazil)
      2. 11.6.2 Company 2 (Mexico)
      3. 11.6.3 Company 3 (Mexico)
    12. Middle East and Africa Chiral Chromatography Column Market Analysis, 2019 - 2023 and Forecast, 2024 - 2031 (Market Value, In USD Mn)
    1. 12.1 By Technique: Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
      1. 12.1.1 High-Performance Liquid Chromatography (HPLC)
      2. 12.1.2 Supercritical Fluid Chromatography (SFC)
      3. 12.1.3 Gas Chromatography (GC)
      4. 12.1.4 Others (Capillary Electrophoresis)
      12.2 By End User: Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
      1. 12.2.1 Pharmaceutical & Biotechnology Companies
      2. 12.2.2 Academic & Research Institutes
      3. 12.2.3 Food & Beverage Testing Labs
      4. 12.2.4 Environmental Testing Labs
      5. 12.2.5 Contract Research Organizations (CROs)
      12.3 Country Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
      1. 12.3.1 Saudi Arabia
      2. 12.3.2 UAE
      3. 12.3.3 South Africa
      4. 12.3.4 Egypt
      5. 12.3.5 Israel
      6. 12.3.6 Rest of Middle East and Africa
    2. 12.4 Middle East and Africa Chiral Chromatography Column Market – Opportunity Analysis Index, By Technique:, By End User:, and Country, 2024 - 2031
    3. 12.5 Regional Trends Analysis
    4. 12.6 Middle East and Africa Chiral Chromatography Column Market Research Report - Company Profiles
      1. 12.6.1 Company 1 (Saudi Arabia)
      2. 12.6.2 Company 2 (UAE)
      3. 12.6.3 Company 3 (UAE)
    13. Competition Landscape
    1. 13.1 Strategic Dashboard of Top Market Players
    2. 13.2 Company Profiles (Introduction, Financial Assessments, Portfolio of Offerings, Milestones and Achievements, Strategic Initiative, and SWOT Analysis)
      1. 13.2.1 Daicel Corporation
      2. 13.2.2 Agilent Technologies
      3. 13.2.3 Merck KGaA
      4. 13.2.4 Thermo Fisher Scientific
      5. 13.2.5 Shimadzu Corporation
      6. 13.2.6 Phenomenex Inc.
      7. 13.2.7 PerkinElmer Inc.
      8. 13.2.8 Waters Corporation
      9. 13.2.9 YMC Co. Ltd.
      10. 13.2.10 Restek Corporation
      11. 13.2.11 Biotage AB
      12. 13.2.12 Gilson Inc.
      13. 13.2.13 Orochem Technologies Inc.
      14. 13.2.14 Aurora Borealis Control BV
      15. 13.2.15 Chiral Technologies Inc.
  1. 14. Data Collection Method and Research Approach
  2. 15. Principal Presumptions and Acronyms