Report Code : CVMI2603252601369 | Published Date : March 30, 2025
1 | Market Overview
The global intraoperative radiation therapy (IORT) market is rapidly expanding due to the increasing prevalence of cancer and the demand for precise, time-efficient treatment options. IORT provides a concentrated dose of radiation directly to the tumor site during surgery, reducing exposure to nearby healthy tissues. It is commonly utilized in treating breast, colorectal, pancreatic, and gynecological cancers.
The integration of IORT into cancer treatment protocols enables clinicians to reduce the number of overall radiation therapy cycles, enhance local tumor control, and improve patient convenience. Advances in technology, such as mobile linear accelerators (LINACs), low-energy X-ray systems, and improved shielding protocols, are increasing the accessibility and effectiveness of IORT procedures.
2 | Market Size and Forecast
Year |
Market Value (USD Billion) |
Notes |
2019 |
1.06 |
Historical benchmark |
2024 |
1.58 |
Five-year CAGR 8.3% |
2031 |
3.06 |
Seven-year CAGR 9.9% |
The market is projected to almost double by 2031, supported by oncology workflow improvements, growing cancer surgical volumes, and innovations in compact IORT delivery systems.
3 | Key Market Drivers
- Rising Cancer Incidence: The global increase in diagnoses of solid tumors, particularly breast and gastrointestinal cancers.
- Demand for Shortened Treatment Cycles: IORT provides single-session radiation, eliminating the need for multi-week external beam therapy (EBRT).
- Advancements in IORT Devices: mobile LINACs, X-ray-based systems, and electron beam IORT platforms.
- Surgeon-Radiation Oncologist Collaboration: Multidisciplinary treatment planning enhances patient outcomes.
4 | Market Challenges
- High equipment and installation costs require specialized infrastructure and shielding.
- Limited Availability of Trained Teams: Requires coordination of surgical and radiation oncology teams.
- Reimbursement Barriers: Coverage differs between markets, particularly in emerging economies.
5 | Competitive Landscape
The IORT market is moderately consolidated, featuring a few major companies alongside several innovative players providing platform-specific solutions.
Market Share Estimates (2024):
Company |
Estimated Market Share |
Key Products |
Carl Zeiss Meditec |
33% |
INTRABEAM® System (X-ray-based IORT) |
S.I.T. Sordina |
21% |
LIAC® HWL and NOVAC® electron IORT systems |
GMV Innovating Solutions |
17% |
Radiance® platform for multidisciplinary OR integration |
IntraOp Medical |
14% |
Mobetron® LINAC system |
Others (Isoray, BrainLab, regional suppliers) |
15% |
Hybrid systems and specialized oncology tools |
6 | Market Segmentation
By Technology:
- Electron Beam IORT
- X-Ray IORT
- Hybrid Systems
By Application:
- Breast Cancer
- Colorectal Cancer
- Gynecological Cancer
- Pancreatic Cancer
- Others (Sarcomas, Head & Neck)
By End User:
- Hospitals
- Specialty Cancer Centers
- Academic & Research Institutes
By Region:
- North America
- Europe
- Asia-Pacific
- Latin America
- Middle East & Africa
7 | Strategic Outlook
IORT is increasingly seen as an integral part of organ-preserving and ambulatory oncology care. Strategic growth will depend on flexible IORT suite designs, bundled device-service models, and evidence-based clinical trials that support broader insurance coverage.
Reasons To Buy

Scope

Key Players
- Carl Zeiss Meditec AG
- IntraOp Medical Corporation
- Elekta AB
- Eckert & Ziegler
- Ariane Medical Systems Ltd.
- Sensus Healthcare Inc
- Sordina IORT Technologies
- iCAD Inc.
- Varian Medical Systems Inc.
- GMV Innovating Solutions
- Isoray Inc.
- Becton Dickinson and Company (BD)
- Brainlab AG
- RaySearch Laboratories AB
- Accuray Incorporated
Intraoperative Radiation Therapy Market Report
- 1. Intraoperative Radiation Therapy Market Research Report
- 1.1 Study Objectives
- 1.2 Intraoperative Radiation Therapy Market - Overview
- 1.3 Reason to Read This Report
- 1.4 Methodology and Forecast Analysis
- 2. Intraoperative Radiation Therapy Market Research Report - Preface
- 2.1 Intraoperative Radiation Therapy Market Research Report – Detailed Scope and Definitions
- 2.1.1 By Technology:
- 2.1.2 By Application:
- 2.1.3 By End User:
- 2.1.4 By Region
- 2.1 Intraoperative Radiation Therapy Market Research Report – Detailed Scope and Definitions
- 3. Intraoperative Radiation Therapy Market Dynamics
- 3.1. Drivers - Macro-Economic Based, Supply Side, and Demand Side Drivers
- 3.2. Restraints – By Technology:, By Application:, By End User:, By Country
- 3.3. Opportunities – By Technology:, By Application:, By End User:, By Country
- 3.4. Trends – By Technology:, By Application:, By End User:, By Country
- 3.5. PEST Analysis
- 3.6. Porters Five Rule Analysis
- 3.7. Company’s Share Analysis (CSA) by Region or By Country
- 3.8. Intraoperative Radiation Therapy Market Research Report – DROTs Impact Analysis
-
- 4. Intraoperative Radiation Therapy Market Research Report, Historic Data 2019 - 2023 and Forecast Analysis Data 2024 - 2031
- 4.1. Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 4.2. Annual Market Trend Assessment – Year-on-Year (YoY) Growth Analysis (%)
- 4.3. Incremental Market Value/Volume Opportunity between 2019 - 2023 and 2024 - 2031
- 4.4. Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 5. Intraoperative Radiation Therapy Market, By Technology:, 2019 - 2023 and Forecast, 2024 - 2031 (Market Value, In USD Mn)
- 5.1 Electron Beam IORT
- 5.1.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 5.1.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 5.1.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 5.1.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 5.2 X-Ray IORT
- 5.2.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 5.2.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 5.2.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 5.2.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 5.3 Hybrid Systems
- 5.3.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 5.3.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 5.3.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 5.3.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 6.1 Breast Cancer
- 6.1.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 6.1.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 6.1.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 6.1.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 6.2 Colorectal Cancer
- 6.2.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 6.2.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 6.2.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 6.2.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 6.3 Gynecological Cancer
- 6.3.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 6.3.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 6.3.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 6.3.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 6.4 Pancreatic Cancer
- 6.4.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 6.4.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 6.4.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 6.4.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 6.5 Others (Sarcomas, Head & Neck)
- 6.5.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 6.5.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 6.5.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 6.5.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 7.1 Hospitals
- 7.1.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 7.1.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 7.1.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 7.1.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 7.2 Specialty Cancer Centers
- 7.2.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 7.2.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 7.2.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 7.2.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 7.3 Academic & Research Institutes
- 7.3.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 7.3.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 7.3.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 7.3.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 8. Intraoperative Radiation Therapy Market Forecast, By Region, 2019 - 2023 and 2024 - 2031 (Market Value, In USD Mn)
- 8.1 North America
- 8.1.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 8.1.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 8.1.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 8.1.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 8.2.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 8.2.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 8.2.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 8.2.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 8.3.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 8.3.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 8.3.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 8.3.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 8.4.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 8.4.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 8.4.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 8.4.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 8.5.1 Market Performance Review & Future Outlook: Assessing 2019 - 2023 and Predicting 2024 - 2031 Trends (USD Millions)
- 8.5.2 Annual Market Trend Assessment – Yearly Growth Observation (Y-O-Y)(%)
- 8.5.3 Incremental Market Value/Volume Opportunity between 2019 - 2023 and From 2024 to 2031
- 8.5.4 Market Shares Analysis in Years - 2019, 2023, 2024 and 2031
- 8.1 North America
- 9. North America Intraoperative Radiation Therapy Market Analysis, 2019 - 2023 and Forecast, 2024 - 2031 (Market Value, In USD Mn)
- 9.1 By Technology: Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
- 9.1.1 Electron Beam IORT
- 9.1.2 X-Ray IORT
- 9.1.3 Hybrid Systems
- 9.2.1 Breast Cancer
- 9.2.2 Colorectal Cancer
- 9.2.3 Gynecological Cancer
- 9.2.4 Pancreatic Cancer
- 9.2.5 Others (Sarcomas, Head & Neck)
- 9.3.1 Hospitals
- 9.3.2 Specialty Cancer Centers
- 9.3.3 Academic & Research Institutes
- 9.4.1 United States
- 9.4.2 Canada
- 9.5 North America Intraoperative Radiation Therapy Market – Opportunity Analysis Index, By Technology:, By Application:, By End User:, and Country, 2024 - 2031
- 9.6 Regional Trends Analysis
- 9.7 North America Intraoperative Radiation Therapy Market Research Report - Company Profiles
- 9.7.1 Company 1 (United States)
- 9.7.2 Company 2 (Canada)
- 9.7.3 Company 3 (Canada)
- 10.1 By Technology: Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
- 10.1.1 Electron Beam IORT
- 10.1.2 X-Ray IORT
- 10.1.3 Hybrid Systems
- 10.2.1 Breast Cancer
- 10.2.2 Colorectal Cancer
- 10.2.3 Gynecological Cancer
- 10.2.4 Pancreatic Cancer
- 10.2.5 Others (Sarcomas, Head & Neck)
- 10.3.1 Hospitals
- 10.3.2 Specialty Cancer Centers
- 10.3.3 Academic & Research Institutes
- 10.4.1 Germany
- 10.4.2 United Kingdom
- 10.4.3 France
- 10.4.4 Spain
- 10.4.5 Italy
- 10.4.6 Russia
- 10.5 Europe Intraoperative Radiation Therapy Market – Opportunity Analysis Index, By Technology:, By Application:, By End User:, and Country, 2024 - 2031
- 10.6 Regional Trends Analysis
- 10.7 Europe Intraoperative Radiation Therapy Market Research Report - Company Profiles
- 10.7.1 Company 1 (Germany)
- 10.7.2 Company 2 (United Kingdom)
- 10.7.3 Company 3 (United Kingdom)
- 11.1 By Technology: Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
- 11.1.1 Electron Beam IORT
- 11.1.2 X-Ray IORT
- 11.1.3 Hybrid Systems
- 11.2.1 Breast Cancer
- 11.2.2 Colorectal Cancer
- 11.2.3 Gynecological Cancer
- 11.2.4 Pancreatic Cancer
- 11.2.5 Others (Sarcomas, Head & Neck)
- 11.3.1 Hospitals
- 11.3.2 Specialty Cancer Centers
- 11.3.3 Academic & Research Institutes
- 11.4.1 China
- 11.4.2 Japan
- 11.4.3 India
- 11.4.4 South Korea
- 11.4.5 Australia & New Zealand
- 11.4.6 ASEAN
- 11.5 Asia-Pacific Intraoperative Radiation Therapy Market – Opportunity Analysis Index, By Technology:, By Application:, By End User:, and Country, 2024 - 2031
- 11.6 Regional Trends Analysis
- 11.7 Asia-Pacific Intraoperative Radiation Therapy Market Research Report - Company Profiles
- 11.7.1 Company 1 (China)
- 11.7.2 Company 2 (Japan)
- 11.7.3 Company 3 (Japan)
- 12.1 By Technology: Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
- 12.1.1 Electron Beam IORT
- 12.1.2 X-Ray IORT
- 12.1.3 Hybrid Systems
- 12.2.1 Breast Cancer
- 12.2.2 Colorectal Cancer
- 12.2.3 Gynecological Cancer
- 12.2.4 Pancreatic Cancer
- 12.2.5 Others (Sarcomas, Head & Neck)
- 12.3.1 Hospitals
- 12.3.2 Specialty Cancer Centers
- 12.3.3 Academic & Research Institutes
- 12.4.1 Brazil
- 12.4.2 Mexico
- 12.4.3 Argentina
- 12.4.4 Peru
- 12.4.5 Colombia
- 12.4.6 Rest of Latin America
- 12.5 Latin America Intraoperative Radiation Therapy Market – Opportunity Analysis Index, By Technology:, By Application:, By End User:, and Country, 2024 - 2031
- 12.6 Regional Trends Analysis
- 12.7 Latin America Intraoperative Radiation Therapy Market Research Report - Company Profiles
- 12.7.1 Company 1 (Brazil)
- 12.7.2 Company 2 (Mexico)
- 12.7.3 Company 3 (Mexico)
- 13.1 By Technology: Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
- 13.1.1 Electron Beam IORT
- 13.1.2 X-Ray IORT
- 13.1.3 Hybrid Systems
- 13.2.1 Breast Cancer
- 13.2.2 Colorectal Cancer
- 13.2.3 Gynecological Cancer
- 13.2.4 Pancreatic Cancer
- 13.2.5 Others (Sarcomas, Head & Neck)
- 13.3.1 Hospitals
- 13.3.2 Specialty Cancer Centers
- 13.3.3 Academic & Research Institutes
- 13.4.1 Saudi Arabia
- 13.4.2 UAE
- 13.4.3 South Africa
- 13.4.4 Egypt
- 13.4.5 Israel
- 13.4.6 Rest of Middle East and Africa
- 13.5 Middle East and Africa Intraoperative Radiation Therapy Market – Opportunity Analysis Index, By Technology:, By Application:, By End User:, and Country, 2024 - 2031
- 13.6 Regional Trends Analysis
- 13.7 Middle East and Africa Intraoperative Radiation Therapy Market Research Report - Company Profiles
- 13.7.1 Company 1 (Saudi Arabia)
- 13.7.2 Company 2 (UAE)
- 13.7.3 Company 3 (UAE)
- 14.1 Strategic Dashboard of Top Market Players
- 14.2 Company Profiles (Introduction, Financial Assessments, Portfolio of Offerings, Milestones and Achievements, Strategic Initiative, and SWOT Analysis)
- 14.2.1 Carl Zeiss Meditec AG
- 14.2.2 IntraOp Medical Corporation
- 14.2.3 Elekta AB
- 14.2.4 Eckert & Ziegler
- 14.2.5 Ariane Medical Systems Ltd.
- 14.2.6 Sensus Healthcare Inc.
- 14.2.7 Sordina IORT Technologies
- 14.2.8 iCAD Inc.
- 14.2.9 Varian Medical Systems Inc.
- 14.2.10 GMV Innovating Solutions
- 14.2.11 Isoray Inc.
- 14.2.12 Becton Dickinson and Company (BD)
- 14.2.13 Brainlab AG
- 14.2.14 RaySearch Laboratories AB
- 14.2.15 Accuray Incorporated
- 9.1 By Technology: Analysis 2019 - 2023 and Forecast, 2024 - 2031 by Market Assessment (USD Mn), Yearly Growth Rate (%), and Market Presence (%)
- 15. Data Collection Method and Research Approach
- 16. Principal Presumptions and Acronyms